South Carolina Gamecocks at Vanderbilt Commodores (+6.5, 45)
The Gamecocks have won nine of 11 games against Vanderbilt in Nashville. The road team is 6-2-1 ATS in their last nine meetings.
Boise State Broncos at Michigan State Spartans (-6.5, 46.5)
Boise State and Michigan State have never met – the Broncos lost to Wisconsin in 1997 in their lone game against a Big Ten school and the Spartans are 7-2 against current members of the Mountain West. The Spartans have won 11 consecutive home openers since falling to Colorado State in 1998.
San Jose State Spartans at Stanford Cardinal (-26, 51.5)
Stanford has won the last four meetings since suffering a humbling 35-34 loss to the Spartans in 2006. The Cardinal lead the series 50-14-1. Spartans are 0-4 ATS in their last four meetings and 0-7 ATS in their last seven games in Stanford.
Notre Dame Fighting Irish vs. Navy Midshipmen (+15.5, 56.5)
After losing to Navy 35-17 in 2010 – a second straight loss to the Midshipmen – Notre Dame rebounded with an impressive 56-14 victory last season, it’s biggest blowout in 2011. Midshipmen are 9-2 ATS in their last 11 games as underdogs.
Buffalo Bulls at Georgia Bulldogs (-37.5, 53.5)
The Bulls are 0-3 against current SEC schools. Buffalo won its last game against a Top 25 team, upending No. 12 Ball State in the 2008 MAC championship game 42-24. The Bulls are 1-7 ATS in their last eight non-conference games.
Marshall Thundering Herd at West Virginia Mountaineers (-24.5, 65.5)
West Virginia has won all 11 meetings against Marshall, however, the Thundering Herd are 4-1 ATS in the last five meetings. The Herd has not defeated a ranked opponent since a win over No. 6 Kansas in 2003, a span of 13 consecutive losses.
Bowling Green Falcons at Florida Gators (-28.5, 48)
The Falcons are 3-6 against ranked teams since 2003, with the last victory coming at No. 25 Pittsburgh in 2008. The Falcons are 12-5-1 ATS in their last 18 games as road underdogs.
Southern Mississippi Golden Eagles at Nebraska Cornhuskers (-20, 53)
Since losing the first game of the 1985 season to Florida State, Nebraska has won each of its next 26 season openers by double figures.
Clemson Tigers at Auburn Tigers (+3.5, 55.5)
Clemson has won 21 of its last 27 season openers and seven of its last 10. The Tigers' three opening losses in the past decade have come against top-25 teams. Auburn has won its last six openers and is 92-25-2 all-time in opening games.
North Texas Mean Green at Louisiana State Tigers (-42.5, 52)
During its 37-game non-conference win streak in the regular season, LSU has outscored opponents 1,479-391, including a 1,163-236 margin at home. Over is 4-1 in Tigers' last five non-conference games.
Hawaii Warriors at USC Trojans (-40, 62.5)
USC is 7-0 against Hawaii and notched a 49-36 victory in 2010 in the most-recent meeting. The Trojans are 28-12 ATS in their last 40 non-conference games.
Wyoming Cowboys at Texas Longhorns (-30, 51)
Texas is 99-17-3 (.845) in openers, including a 77-7-2 (.907) mark at home. Brown has won 13 of his 14 openers at Texas. Cowboys are 13-3 ATS in their last 16 games as road underdogs.
Michigan Wolverines at Alabama Crimson Tide (-14, 45.5)
Michigan is 24-9-1 against current SEC teams, but the Wolverines haven't faced an SEC opponent in the regular season since 2006. Over is 7-1 in Wolverines' last eight versus SEC foes.
Arkansas State Red Wolves at Oregon Ducks (-35, 68.5)
The Ducks averaged 46.1 points, third in the nation last season. Over is 21-4-1 in Ducks' last 26 games as home favorites.
Oklahoma Sooners at UTEP Miners (+31, 61.5)
Oklahoma has won the two previous meetings - 55-14 in 2000 and 68-0 in 2002 - both in Norman. The Sooners are 5-0 ATS in their last five non-conference games.
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